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CIBINQO (abrocitinib) is a prescription medicine to treat adults with moderate-to-severe eczema (atopic dermatitis) that did not respond to other treatment and is not well controlled with prescription medicines, including biologics, or when they cannot be tolerated.
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ABOUT ECZEMA (atopic dermatitis)
If your eczema (atopic dermatitis) feels like a burden, you should know you’re not alone. In fact, there are about 6.6 million adults living with moderate-to-severe eczema in the U.S. right now.
It's also common to have difficulty managing your condition. In one study, about 200 doctors surveyed found that nearly 59% of patients with moderate-to-severe eczema were not well controlled.
In the U.S. alone, about
adults have moderate-to-severe eczema
If your eczema (atopic dermatitis) feels like a burden, you should know you’re not alone. In fact, there are about 6.6 million adults living with moderate-to-severe eczema in the U.S. right now.
It's also common to have difficulty managing your condition. In one study, about 200 doctors surveyed found that nearly 59% of patients with moderate-to-severe eczema were not well controlled.
You’ve probably learned a lot about eczema already. But thanks to recent information and research, you may want to take a fresh look at its
potential causes and symptoms. The more you know, the more prepared you can be to have meaningful conversations with your doctor about your treatment options.
A study of 1,064
Eczema can look and feel different from person to person. The signs and symptoms of moderate-to-severe eczema may include:
Eczema may look different on different skin tones.
In lighter skin tones, eczema often looks red.
In darker skin tones, eczema may appear as darker patches, and redness may not be as visible.
In lighter skin tones, eczema often looks red.
In darker skin tones, eczema may appear as darker patches,
In a study of 602 people with eczema,
If you have eczema, you can see it’s a skin condition. You've probably also learned it may be
IRREGULAR IMMUNE RESPONSE
Eczema can be caused in part by
INFLAMMATION
This immune response is
SIGNS OF ECZEMA
Inflammation contributes to
If you are like many people with moderate-to-severe eczema, you may have struggled with your condition.
Talk to your doctor if your eczema feels uncontrolled, even with prescription topical medicine.
Be sure to tell your doctor about your symptoms and the signs of eczema on your skin’s surface. Also talk about any impact of eczema they may not see, like loss of sleep. This can help your doctor recommend a treatment plan that’s right for you.
A study of 1,064
If you are like many people with moderate-to-severe eczema, you may have struggled with your condition.
Talk to your doctor if your eczema feels uncontrolled, even after you've tried other medicines, including biologics.
Be sure to tell your doctor about your eczema signs and symptoms. This can help them recommend a treatment plan that's right for you.
Thinking about talking We’ll help you track symptoms, consider your goals, and note questions to ask—whether your conversation is virtual or in person.
There can be more to eczema than meets the eye
6.6 MILLION
If you struggle with this chronic
condition, you are not alone
When it comes to your eczema,
stay informed
people showed
do not have control over
their moderate-to-severe
eczema
Which signs and symptoms do
you experience?
and redness may not be as visible.
among the 206 who describe their eczema
as moderate or severe
What causes eczema?
caused by various factors, such as your genes or triggers in your environment.
But did you know
your immune system and inflammation may also play a role?
an irregular immune response
within the skin.
thought to contribute to
inflammation in the skin.
the signs of eczema you see
on the skin’s surface.
Every person is different. What’s the
next step for you?
people showed
struggle to control their
moderate-to-severe
eczema
with your doctor?
Get our full guide for talking with your doctor
CIBINQO may cause serious side effects, including:
Serious infections. CIBINQO can lower your immune system’s ability to fight infections. Do not start CIBINQO if you have any kind of infection unless your healthcare provider tells you it is okay. Serious infections, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that can spread throughout the body, have occurred in people taking CIBINQO or other similar medicines. Some people have died from these infections. Your risk of developing shingles may increase while taking CIBINQO.
Your healthcare provider should test you for TB before treatment with CIBINQO and monitor you closely for signs and symptoms of TB infection during treatment.
Before and after starting CIBINQO, tell your doctor right away if you have an infection, are being treated for one, or have symptoms of an infection, including:
CIBINQO can make you more likely to get infections or worsen infections you have.
There is an increased risk of death in people 50 years and older who have at least one heart disease (cardiovascular) risk factor and are taking a Janus kinase (JAK) inhibitor (such as CIBINQO).
Cancer and immune system problems. CIBINQO may increase your risk of certain cancers by changing the way your immune system works. Lymphoma and other cancers, including skin cancers, can happen. People, especially current or past smokers, have a higher risk of certain cancers, including lymphoma and lung cancers, while taking a JAK inhibitor. Follow your healthcare provider’s advice about having your skin checked for skin cancer during treatment. Limit the amount of time you spend in sunlight and avoid using tanning beds or sunlamps. When in the sun, wear protective clothing and use SPF 30+ sunscreen. This is especially important if you have very fair skin or a family history of skin cancer. Tell your healthcare provider if you have ever had any type of cancer.
There is an increased risk of major cardiovascular (CV) events such as heart attack, stroke or death in people 50 years and older who have at least one heart disease (CV) risk factor and are taking a JAK inhibitor, especially for current or past smokers.
Some people taking CIBINQO have had major cardiovascular events.
Get emergency help right away if you develop any symptoms of a heart attack or stroke while taking CIBINQO, including:
Blood clots. Blood clots in the veins of your legs (deep vein thrombosis, DVT) or lungs (pulmonary embolism, PE) can happen in some people taking CIBINQO. This may be life-threatening. Blood clots in the veins of the legs and lungs have happened more often in people 50 years and older, with at least one heart disease (CV) risk factor, taking a JAK inhibitor. Tell your healthcare provider if you have had blood clots in the veins of your legs or lungs in the past.
Get medical help right away if you have any signs and symptoms of blood clots including swelling, pain, or tenderness in one or both legs; sudden, unexplained chest or upper back pain; shortness of breath or difficulty breathing.
Changes in certain laboratory test results. Your doctor should do blood tests before and during treatment with CIBINQO to check your lymphocyte, neutrophil, red blood cell, and platelet counts. You should not take CIBINQO if these counts are too low. Your healthcare provider may stop treatment for a period of time if there are changes in these blood test results. You may also have changes in other laboratory tests, such as your blood cholesterol levels. Your doctor should do blood tests about 4 weeks after you start treatment and 4 weeks after any increase in dose to check blood cell counts and as often as needed for other laboratory tests.
During the first 3 months of treatment with CIBINQO, do not take medicines that prevent blood clots except low-dose aspirin (≤81 mg daily), if prescribed.
Before taking CIBINQO, tell your healthcare provider if you:
The most common side effects of CIBINQO include common cold, nausea, headache, herpes simplex including cold sores, increased blood level of creatinine phosphokinase, dizziness, urinary tract infection, tiredness, acne, vomiting, mouth and throat pain, flu, stomach flu, bacterial skin infection, high blood pressure, allergic skin rash to something you contacted, stomach pain, shingles, and low platelet count.
CIBINQO may cause fertility problems in females, which may affect the ability of females to get pregnant. Talk to your healthcare provider if you have concerns about fertility.
Separation or tear to the lining of the back part of the eye (retinal detachment) has happened in people treated with CIBINQO. Call your healthcare provider right away if you have any sudden changes in your vision.
These are not all of the possible side effects of CIBINQO.
What is CIBINQO?
CIBINQO is a prescription medicine to treat adults with moderate-to-severe eczema (atopic dermatitis) that did not respond to other treatment and is not well controlled with prescription medicines, including biologics, or when they cannot be tolerated.
It is not known if CIBINQO is safe and effective in children.
Please see full Prescribing Information, including BOXED WARNING, and Medication Guide.
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If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088.
You are encouraged to report adverse events related to Pfizer products by calling
1-800-438-1985 (U.S. only).
If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088.
CIBINQO may cause serious side effects, including:
Serious infections. CIBINQO can lower your immune system’s ability to fight infections. Do not start CIBINQO if you have any kind of infection unless your healthcare provider tells you it is okay. Serious infections, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that can spread throughout the body, have occurred in people taking CIBINQO or other similar medicines. Some people have died from these infections. Your risk of developing shingles may increase while taking CIBINQO.
Your healthcare provider should test you for TB before treatment with CIBINQO and monitor you closely for signs and symptoms of TB infection during treatment.
Before and after starting CIBINQO, tell your doctor right away if you have an infection, are being treated for one, or have symptoms of an infection, including:
CIBINQO can make you more likely to get infections or worsen infections you have.
There is an increased risk of death in people 50 years and older who have at least one heart disease (cardiovascular) risk factor and are taking a Janus kinase (JAK) inhibitor (such as CIBINQO).
Cancer and immune system problems. CIBINQO may increase your risk of certain cancers by changing the way your immune system works. Lymphoma and other cancers, including skin cancers, can happen. People, especially current or past smokers, have a higher risk of certain cancers, including lymphoma and lung cancers, while taking a JAK inhibitor. Follow your healthcare provider’s advice about having your skin checked for skin cancer during treatment. Limit the amount of time you spend in sunlight and avoid using tanning beds or sunlamps. When in the sun, wear protective clothing and use SPF 30+ sunscreen. This is especially important if you have very fair skin or a family history of skin cancer. Tell your healthcare provider if you have ever had any type of cancer.
There is an increased risk of major cardiovascular (CV) events such as heart attack, stroke or death in people 50 years and older who have at least one heart disease (CV) risk factor and are taking a JAK inhibitor, especially for current or past smokers.
Some people taking CIBINQO have had major cardiovascular events.
Get emergency help right away if you develop any symptoms of a heart attack or stroke while taking CIBINQO, including:
Blood clots. Blood clots in the veins of your legs (deep vein thrombosis, DVT) or lungs (pulmonary embolism, PE) can happen in some people taking CIBINQO. This may be life-threatening. Blood clots in the veins of the legs and lungs have happened more often in people 50 years and older, with at least one heart disease (CV) risk factor, taking a JAK inhibitor. Tell your healthcare provider if you have had blood clots in the veins of your legs or lungs in the past.
Get medical help right away if you have any signs and symptoms of blood clots including swelling, pain, or tenderness in one or both legs; sudden, unexplained chest or upper back pain; shortness of breath or difficulty breathing.
Changes in certain laboratory test results. Your doctor should do blood tests before and during treatment with CIBINQO to check your lymphocyte, neutrophil, red blood cell, and platelet counts. You should not take CIBINQO if these counts are too low. Your healthcare provider may stop treatment for a period of time if there are changes in these blood test results. You may also have changes in other laboratory tests, such as your blood cholesterol levels. Your doctor should do blood tests about 4 weeks after you start treatment and 4 weeks after any increase in dose to check blood cell counts and as often as needed for other laboratory tests.
During the first 3 months of treatment with CIBINQO, do not take medicines that prevent blood clots except low-dose aspirin (≤81 mg daily), if prescribed.
Before taking CIBINQO, tell your healthcare provider if you:
The most common side effects of CIBINQO include common cold, nausea, headache, herpes simplex including cold sores, increased blood level of creatinine phosphokinase, dizziness, urinary tract infection, tiredness, acne, vomiting, mouth and throat pain, flu, stomach flu, bacterial skin infection, high blood pressure, allergic skin rash to something you contacted, stomach pain, shingles, and low platelet count.
CIBINQO may cause fertility problems in females, which may affect the ability of females to get pregnant. Talk to your healthcare provider if you have concerns about fertility.
Separation or tear to the lining of the back part of the eye (retinal detachment) has happened in people treated with CIBINQO. Call your healthcare provider right away if you have any sudden changes in your vision.
These are not all of the possible side effects of CIBINQO.
What is CIBINQO?
CIBINQO is a prescription medicine to treat adults with moderate-to-severe eczema (atopic dermatitis) that did not respond to other treatment and is not well controlled with prescription medicines, including biologics, or when they cannot be tolerated.
It is not known if CIBINQO is safe and effective in children.
Please see full Prescribing Information, including BOXED WARNING, and Medication Guide.
